As for something that doesn't exactly fit your bill, but there is House and Wilson and bloodsucking (and it is just insanely great): Distress Call (http://black-cigarette.livejournal.com/47299.html) by the black_cigarette collective. It's friendship (at least supposed to be? hee) and science-fiction and it takes the whole supernatural concept of "vampire" and turns it into something natural and real and fantastically thought out.